What Is KPV?

KPV (Lys-Pro-Val) is a tripeptide fragment of alpha-melanocyte-stimulating hormone (α-MSH). It is studied for potent anti-inflammatory, antimicrobial, and wound-healing activity, with common research interest in immune modulation, skin health, and gut inflammation management.

Mechanisms of Action

Anti-inflammatory action that inhibits pro-inflammatory cytokines such as TNF-α and IL-6, reducing systemic and localized inflammation.
Wound healing and tissue repair activity that promotes tissue regeneration and may reduce oxidative stress and scarring signals.
Antimicrobial effects with broad-spectrum activity against bacteria, fungi, and other pathogens, supporting immune defense and infection control.

Benefits

Skin health and inflammatory skin condition research interest, including models relevant to eczema, psoriasis, acne, and related inflammatory presentations.
Gut health and inflammation management interest, including gastrointestinal inflammation models such as IBD, ulcerative colitis, and Crohn’s disease.
Tissue repair and wound healing interest, supporting faster healing and reduced scarring signals in post-surgical recovery and injury repair models.

Dosing

Route	Dose
Oral	500 mcg per capsule, typically taken 1 to 2 times daily
Subcutaneous injection	200 to 500 mcg daily, used for systemic inflammation control and immune modulation models

Safety Profile

KPV is generally described as well tolerated, with minimal adverse effects reported in research discussions.

Topical use is commonly considered compatible with most skin types, with monitoring advised in sensitive skin contexts.
Systemic use is typically characterized as having a favorable safety profile in the research literature.

Stacking

Repair & Recovery Stack

KPV
GHK-Cu
BPC-157
TB-500
Glutathione

Disclaimer: The information provided is intended solely for educational purposes and should not be considered a replacement for professional medical advice. All compounds referenced are not for human consumption.